This parish was established by Jesuits Missionaries in 1663. Santo Nino de Ternate was installed as its titular patron saint after the Mardicas (first settlers of Ternate arrived in Ternate from Mollucas Island) brought with them the Holy Image of Santo Nino de Ternate. The Holy Image of Santo Nino de Ternate is now enshrined in the Roman Catholic Church of Ternate.